Secondary Metabolites, Other Prospective Substances, and Alternative Approaches That Could Promote Resistance against Phytophthora infestans

Potato (Solanum tuberosum) is a valuable staple crop that provides nutrition for large part of the human population around world. However, domestication process reduced its resistance to pests and pathogens. Phytophthora infestans, causal agent late blight disease, most destructive pathogen potato plants. Considerable efforts have been made develop blight-resistant cultivars, but success has limited present-day production requires extensive use fungicides. In this review, we summarize known sources obstacles in P. infestans control. We outline problematic aspects chemical treatment, possible biological control, available resources natural wild Solanum accessions. focus on prospective putative markers are often overlooked genome-centered studies, including secondary metabolites from alkaloid, phenylpropanoid, terpenoid classes, lipids, proteins, peptides. discuss suitability these molecules marker-assisted selection possibility increasing speed conventional breeding more resilient cultivars.